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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company focuses on the discovery of biological, small molecule and genetic therapeutics for the treatment of diabetes, obesity and associated complications. We are seeking a skilled and motivated in vitro biologist to join our drug discovery and development team in the Dyslipidemia and New Modality research group in Indianapolis. The successful candidate will use strong molecular and cellular biology skills to initiate discovery efforts and support pipeline projects. The focus will be on therapeutics targeting obesity, metabolic disease, and dyslipidemia. You should have extensive experience in developing and implementing in vitro and cellular assays. Responsibilities include establishing critical lab capabilities and collaborating with other scientists within and across departments to achieve project and department goals.

Do you have experience with cellular and molecular biology? Apply today to join the Lilly Team!

Responsibilities

• Plan and implement in vitro and cell-based experiments independently. Support preclinical characterization and evaluation of relevant targets and pathways using CRISPR technologies.

• Perform molecular and biochemical assessments on samples from tissues and cells including RNA/gDNA isolation and analysis, gene and protein expression analyses, and other analytical techniques.

• Demonstrate the ability to work independently with high ownership and accountability. Show initiative and a record of success within cross-functional project teams.

• Be adaptable, showing capability to establish new techniques, learn new biology, and quickly pivot in a data-driven environment.

Minimum requirements

• BS or MS with 5+ years of experience

Additional Skills/Preferences

• Experience with cellular and molecular biology and in vitro assay development in the pharmaceutical industry

• Proficiency in a wide array of cell biology techniques including cell culture, transfection, FACS, and other cell-based assays

• Knowledge/hands-on experience in implementation of gene editing methods and analysis including gDNA/RNA isolation, sequencing (Sanger, NGS, long-read), gene expression (qPCR), ddPCR, and protein expression (western, JESS, ELISA, MSD).

• A background in cell/molecular biology of obesity, metabolic disease, and dyslipidemia is a plus

• Experience with complex cell culture systems, primary culture, co-culture, and stable cell line generation

• Experience with various assay detection technologies (fluorescence, luminescence, FRET, alpha-screen, radiometric assays) and ability to implement and validate new technologies

• Support the implementation of new assay technologies

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( LillyRecruitingCompliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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